Artemisia Annua Extract Powder
Basic info
1. Latin Name: Artemisia annua L.
2. Part of used: Natural wormwood dried leaf
3. CAS No.: 63968-64-9
4. Molecular Formula: C15H22O5
5. Molecular Weight: 282.34
6. Appearance: White crystalline fine powder
7. Specification: Artemisinin 98% 99%
Introduction:
Artesunate is used primarily as treatment for malaria; it has also been shown to be >90% efficacious at reducing egg production in Schistosoma haematobium infection.
According to WHO intravenous AS is the drug of choice for severe malaria both in children and adults where there is low transmission.In regions where transmission is high, randomized trials among Asian adults and African children strongly advocates the use of artesunate over quinine as the treatment of choice for falciparum malaria.
Artesunate is prepared from dihydroartemisinin (DHA) by reacting it with succinic acid anhydride in basic medium. Pyridine as base/solvent, sodium bicarbonate in chloroform and catalyst DMAP (N,N-dimethylaminopyridine) and triethylamine in 1,2-dichloroethane have been used, with yields of up to 100%. A large scale process involves treatment of DHA in dichloromethane with a mixture of pyridine, a catalytic amount of DMAP and succinic anhydride. The dichloromethane mixture is stirred for 6-9 h to get artesunate in quantitative yield. The product is further re-crystallized from dichloromethane. alpha-Artesunate is exclusively formed (m.p 135-137C).
Artemisia Annua Extract Extraction Process:
Raw Material → Immersion in water → Filtering → Purification → Concentration in Vacuum → Killing of Bacteria → Drying → Powder
Main Function:
Artesunate is an antimalarial agent. It is a water-soluble hemisuccinate derivative of dihydroartemisinin. Artemisinin is a sesquiterpene lactone isolated from Artemisia annua, a herb that has traditionally been used in China for the treatment of malaria. Artesunate and its active metabolite dihydroartemisinin are potent blood schizonticides, active against the ring stage of the parasite. Artesunate is ideal for the treatment of severe malaria, including cerebral malaria. It is also active against chloroquine and mefloquine resistant strains of P. falciparum.
It is unstable in neutral solution and is therefore only available for injections as artesunic acid. The injectable formulation must be prepared immediately before use in 5% (w/v) sodium bicarbonate solution to produce the salt sodium artesunate
Application:
1. Artemisinin used to kill parasites, particularly worms and flukes;
2. artemisinin is generally well tolerated at the doses used to treat malaria;
3.Artemisinin is used primarily for liver, gall bladder and stomach ailments as well as to expel intestinal
worms.
Anti-oxidation
Astaxanthin (3%,5%)
Lutein (5%,10%,20%)
Lycopene (5%,6%,10% )
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Resveratrol (10%,20%,50%,98%)
Green Tea Extract (50%,95%,98%)
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Phyllanthus Emblica Extract (10:1)
Mangosteen Extract (10%,20%.30%,95%)
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5-HTP/Griffonia Seed Extract (20%-90%)
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CoQ10 (98%)
Huperzine A (1%,5%,98%)
Rhodiola Rosea Extract (3%)
Panax Ginseng Extract (10%-80%)
Valerian Root Extract (0.4%,0.8%)
Horse Chestnut Extract (20%,95%)
Lemon Balm Extract (10:1,3%,5%)
Gastrodia Tuber Extract (10%,20%)
Galanthamine Hydrobromide (99%)
Passion Flower Extract (3%,4%,5%)
Siberian Ginseng Extract (0.8%,1.2%)
Semen Ziziphi Spinosae Extract (2%)
Butcher's Boom Extract (5%,10%,20%)
Menopausal Symptoms
Soybean Extract (20%,40%)
Black Cohosh Extract (2%,2.5%)
Wild Yam Extract (8%,16%,98%)
Chrysanthenmum Extract (10:1,15:1)
Baical Skullcap Root Extract (85%)
Angelica/Dong Quai Extract (10:1,%1)
Kudzu Root(Puerara) Extract (40%,80)
Blood Sugar Blood Fats
Gymnema Extract (25%)
Bitter Melon Extract (10%)
Dogbane Leaf Extract (10:1)
Artichoke Extract (2.5%,5%)
Mulberry Leaf Extract (DNJ1%)
Tartary Buckwheat Extract (10:1)
Celery Seed Extract (1%,10:1,5:1)
Pomegranate Extract (40% Polyphenol)
Garlic Extract (Alliin 2%,5%; Allicin 1%)
Corn Silk Extract (beta sitosterol 5%,10:1)
Salvia Miltiorrhiza Extract (10:1,10%,20%)
Red Yeast Rice Extract (0.1%,0.3%,0.8%,1%)
Corosolic Acid (1%,2%,5%,10%,20%,98%)
Ginkgo Biloba Extract (CP2005,CP2010,USP32)
Mesh size: 100% pass 80 Mesh
Microbiological Control:
| Total Plate Count |
≤1000cfu/g |
| Yeast & Mold |
≤100cfu/g |
| E.Coli |
Negative |
| Salmonella |
Negative |
| Staphylococcus Aureus |
Negative |
Packing & Storage:
Package: 1kg double layer plastic bags inside and aluminum foil bag outside; 25kg/Fibre Drum, or at customer's requirements
Storage: Store in a cool, dry place and keep away from strong light and heat.
Shelf Life: 24 Month when properly stored.
Shipments:
1. Small Orders: by DHL, UPS, TNT, EMS, FedEx, etc.
2. Big orders: by air or sea.
Any questions please feel free contact me soon as. Thanks for your attention. Yours early reply will highly appreciated!
Contact information:
Company:Xi'an Tian Rui Bio-Tech Co., Ltd
Add: No.101-18, Huilinhuacheng, Taiyuan Road, Xi'an city
Contact: Miss. Sherry Wang
About us:
Xi'an Tian Rui Biotech Co., Ltd. is a High-tech Imp & Exp company specializing in the R&D, manufacture and sale of many kinds of purified natural herb extracts. We have a strong R&D team supported by PH.D researchers from some famous universities in China. Our production staff members consist of experienced technicians and managers.
At present, we have already developed more than 100 species of natural compounds from herbs, and we also have advantages in the chemical synthesis of natural products. Your visit will be highly appreciated, and we hope both of us can have an opportunity to make progress together.
Thanks for your attention!
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