Common name: Vinca Rosea Extract
Latin name: Uncaria rhynchophylla(miq.)Jacks /Radix Ranunculus Ternati
Part Used: Herb
Appearance: Brown powder
Ratio: 4:1~20:1 ; Straight Powder
vinblastine (Catharanthine) >95%,
Vinpocetine > 98%
Test Method: HPLC, UV
Introduction of Vinca Rosea Extract:
Vinblastine is a vinca alkaloid and a chemical analogue of vincristine. It binds tubulin, thereby inhibiting the assembly of microtubules. It is M phase cell cycle specific since microtubules are a component of the mitotic spindle and the kinetochore which are necessary for the separation of chromosomes during anaphase of mitosis. Toxicities include bone marrow suppression (which is dose-limiting), gastrointestinal toxicity, potent vesicant (blister-forming) activity, and extravasation injury (forms deep ulcers).
Vinblastine paracrystals may be composed of tightly-packed unpolymerized tubulin or microtubules.
Microtubule disruptive drugs like vinblastine, colcemid, nocodazole have been reported to act by two mechanisms. At very low concentrations they suppress microtubule dynamics and at higher concentrations they reduce microtubule polymer mass. Recent findings indicate that they also produce microtubule fragments by stimulating microtubule minus-end detachment from their organizing centers. Dose-response studies further indicate that enhanced microtubule detachment from spindle poles correlate best with cytotoxicity.
Vinblastine is a component of a number of chemotherapy regimens, including ABVD for Hodgkin lymphoma. It is also used to treat histiocytosis according to the established protocols of the Histiocytosis Association of America.
Function of Vinca Rosea Extract:
1. It has vasodilating, blood thinning, and memory-enhancing actions.
2. It acts as a cerebral stimulant and vasodilator.
3. It is used to treat arteriosclerosis.
4. It is very effective in curing dementia caused due to insufficient blood supply to the brain.
5. It interferes with cells' ability to synthesize DNA and RNA.
Raw Material → Immersion in water → Filtering → Purification → Concentration in Vacuum → Killing of Bacteria → Drying → Powder
Total Plate Count: 10000CFU/g MAX
Yeast & Mold: 100CFU/g MAX
Package: 25kg/Fibre Drum, or at customer's requirements
Storage: Store in a cool, dry place and keep away from direct strong light.
Shelf Life: 2 years
1. What's the payment terms?
T/T ,Paypal, Western Union.
1kg, some special product can be 10grams.
3. What's your lead time?
Usually we arrange the shipment in 1 -3 working days after the payment cleared.
4.What is your sample policy?
Free sample is available while you afford the courier charge.
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